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Weighted UniFrac distance analysis, incorporating phylogenetic and abundance information, confirmed significant dysbiosis in the VPA-ASD model, with the highest dissimilarity from controls (Figure S4E)
Notably, the PNA model mimics a lean phenotype with subtle metabolic alterations and may phenocopy the human phenotype B of PCOS 45 , characterized by hyperandrogenism and oligo-anovulation, with cycle irregularities
Previous literature has highlighted the role of ancestry 11 and T2D status 14 in determining GLP1 medication efficacy for weight loss
Glutathione is one of the most important parts of cellular defense against harmful substances
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