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Key Takeaways Estrogen and GLP-1 medications both improve metabolism
Some users prefer fasting administration on the theory that it reduces interference with absorption, but there is no strong evidence that food significantly affects subcutaneous peptide delivery
And as the city points out, other local governments in Maine never offered employees insurance coverage of GLP-1s for weight loss in the first place
In one-way sensitivity analysis, the ICER remained within 4.30 million to 6.30 million/QALY in the non-T2D cohort and 5.74 million to 8.44 million/QALY in the T2D cohort when key parameters were varied, and no plausible variation changed the direction of incremental costs and QALYs
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