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For biosimilars, the rebate dynamics are different

Sustained, low-level receptor activation could help preserve neuronal glucose utilization and synaptic functioncritical to long-term cognitive health in women after menopause, when estrogens neuroprotective effect wanes

Study designs RCTs, retrospective and prospective observational cohorts, pharmacovigilance disproportionality analyses of spontaneous reporting databases, and case reports or series