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Primary sources Lau et al., Journal of Medicinal Chemistry (2015), DOI 10.1021/acs.jmedchem.5b00726 molecular design, receptor activity, albumin affinity, and experimental pharmacokinetics
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The magnitude of liver fat reduction exceeded predictions based solely on weight loss, suggesting direct hepatic effects beyond indirect benefits of fat mass reduction
However, HCGs use for weight loss is controversial and not FDA-approved for this purpose
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