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Receptor for advanced glycation end products activation injures primary sensory neurons via oxidative stress

Pharmacologic pain management: In accordance with American College of Physicians guidelines, non-steroidal anti-inflammatory drugs (NSAIDs) may be considered first-line when appropriate, using the lowest effective dose for the shortest duration

The idea is that by helping to regulate appetite and reduce the intense focus on food, they might indirectly improve mood and reduce symptoms of depression

Sources and Further Reading: For readers who wish to learn more from official sources, we recommend the following resources