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The primary outcome was MACE, a composite of myocardial infarction, stroke, and all-cause mortality
Suppression of oxidative stress by beta-hydroxybutyrate, an endogenous histone deacetylase inhibitor
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Increased risk of nutrient deficiencies Studies examining rapid weight loss show that severe calorie restriction leads to deficiencies in 4 : Iron Calcium Vitamin D B vitamins (particularly B12) Magnesium Potassium These deficiencies can develop within weeks and manifest as fatigue, hair loss, frequent illness and poor concentration
