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Phase 3: the REDEFINE trials The Phase 3 programme for CagriSema is conducted under the name REDEFINE a series of large, randomised, controlled trials designed to confirm efficacy and establish the safety profile required for regulatory approval

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Materials and methods: Using electronic health record and genetic data from 51,108 British Pakistani and Bangladeshi individuals with T2D (n = 11,673) and GDM (n = 1,965) in the Genes & Health study, we explored associations between pPS, T2D, GDM, diabetes complications, and treatment response using sex- and ancestry-adjusted multivariable regression and Cox proportional-hazards models

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