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I started on B12 injections in March last year, loading doses every other day for two weeks

A 2022 study in Diabetes, Obesity and Metabolism (Friedrichsen et al.) measured voluntary fluid intake in semaglutide patients vs controls and found a 22% reduction in daily water consumption during the first 12 weeks

However, healthcare providers often recommend using the lowest effective dose for the shortest duration possible, as long-term use of PPIs carries its own set of considerations

Weight loss was significant in outcome trials, ranging from a 0.6 kg reduction at 12 weeks in the ELIXA trial to a 4.3 kg reduction at 2 years with injectable semaglutide in the SUSTAIN-6 trial