Therefore, for real-time and in situ monitoring the cellular kinetics of metabolic pathway of glutaminolysis, it is conceivable to employ kinetic models, informed by time series, conventional biochemical models such as the pH extracellular assay (measures the lactate production rate), as the basis on which multivariate data mining techniques such as MCR-ALS can reliably extract the signatures of interest from label-free, Raman microspectroscopic analysis of live cells, and interpret them in terms of their biochemical origin
Chan TC, Wilkinson Berka JL, Deliyanti D, Hunter D, Fung A, Liew G, White A
It stimulates the breakdown of stored fat, particularly visceral fat, which contributes to a more defined and leaner body composition
our study demonstrated that combination therapy was associated with a 55% reduction in mortality