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Skov-Jeppesen K, Svane MS, Martinussen C, et al
N Engl J Med 352, 20-28.), 3 anti-inflammatory therapy targeting the IL-1 innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level lowering (Ridker, P
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