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The reduced Cyp2e1 expression means acetaldehyde (the toxic intermediate product of alcohol metabolism) may accumulate to higher levels before being converted to acetate
This is why timing is important but small changes can be safe and usually will not harm most people
But one question looms large for anyone starting on this treatment path: how quickly do the injections start to work, and what factors influence their effectiveness
Some patients report feeling refreshed or more energized after a B12 shot, while others may notice changes gradually over time
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