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10.4103/NRR.NRR-D-24-00112 125 ZhuX.LuH.JiaH.WeiX.XueJ.LiW.et al (2025)
A pharmacokinetic study in rats found that oral administration produced substantial plasma concentrations, with a maximum concentration of 2252 ng/mL and an elimination half-life of approximately 6.9 hours
As a non-selenocysteine, GPx8 is a membrane protein that is detected in the endoplasmic reticulum, is present abundantly expressed in the lung, and was identified as a novel member of the GPx family [23]
Immunogenicity of therapeutic proteins: clinical implications and future prospects
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