[0035] Add 2-aminoisobutyric acid (1.24g, 12.0mmol), triethylamine (1.21g, 12.0mmol), dichloromethane (20mL) into the reaction flask, lower to 0C, add the above compound III (4.32g, 10.0 mmol) was incubated for reaction, and after TLC detected that the reaction was complete, water (20 mL) was added to the reaction system and stirred for 10 minutes, the organic phase was collected, and concentrated under reduced pressure until no liquid flowed out
While the release does not mention Hims & Hers directly, it establishes Novos position, condemning the compounded copycats
Additionally, the company has lowered the prices of its existing 2.5 mg and 5 mg vials by $50 to $349 and $499 per month, respectively
In head-to-head research, tirzepatide has consistently demonstrated greater average weight loss compared to semaglutide