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Over time, needles become dull and may develop small imperfections, which can tear tissue instead of piercing it cleanly
This can trigger a feedback cycle where the body is stuck in a stress response state
Colloids Surf B Biointerf (2020) 188:110762
When there is a severe insult to the liver, the liver cells can die, and we can see this in a blood test when we look at the inflammation in the liver. In severe cases, people can die from liver failure or they need a liver transplant to save their life. That patient is unlikely to need a transplant
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