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Read on NEJM STEP 4 Rubino et al., Nat Med 2022 Two-year extension showing sustained weight loss , continued reductions in CRP , and improved insulin sensitivity , underscoring durable anti-inflammatory and metabolic benefits

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Suboxone, which contains buprenorphine and naloxone, and Subutex, which contains buprenorphine, attach to the brains opioid receptors

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