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If metformin is contraindicated or not tolerated (including trying the modified-release preparation to reduce the risk of gastrointestinal disturbance), then any of the four treatments mentioned above, including SGLT2 inhibitors, are options as monotherapy for glycaemic control (NICE, 2016a
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You should also keep an eye on any redness or sensitivity around the injection site
In 2026, the FDA approved a new higher dose of Wegovy that may help some patients lose more weight
