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Because tirzepatide activates the GIP receptor in addition to the GLP-1 receptor that semaglutide targets, it produces a broader metabolic effect, including stronger appetite suppression, improved insulin sensitivity, and enhanced fat oxidation
doi:10.1210/jcem.87.4.8421 Zheng H, Wei J, Wang L, et al
Some mild side effects may include temporary discomfort at the injection site or slight bruising, but these are typically short-lived
A cortisone injection reduces swelling, dampens the immune response at the injection site, and provides pain relief -- often within days
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