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Cartilage faces even greater obstacles given avascular nature (no blood vessels penetrating tissue), low cell density (chondrocytes sparse within extensive extracellular matrix), minimal metabolic activity (slow turnover and repair), and mechanical loading challenges (constant stress impeding healing)

These proteins play roles in healing wounds, promoting cell development, and combating inflammation

This modulation reduces inflammatory cytokines and promotes a window in which sperm can survive

This study suggests that DSIP may have geroprotective and anti-cancer properties, making it a potential peptide of interest for longevity research