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Irritation, when it occurs, is usually attributable to co-formulants such as penetration enhancers, preservatives, or residual solvents rather than the peptide itself
It activates amylin receptors in the brain to regulate satiety, gastric emptying, and glucose homeostasis
Mechanisms by which glucose utilization inhibits fatty acid oxidation are tissue specific due primarily to the differences in K m of hepatic glucokinase and skeletal muscle and adipose tissue hexokinase
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