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In many studies, ROS-induced apoptosis is linked to cytochrome C release and caspase-3/9 9 (CASP3/9) activation [86,87,88]
A 2023 study published in JAMA Ophthalmology examined over 16,000 patients and found a small but statistically significant increased risk of certain retinal complications in those prescribed semaglutide compared to other diabetes medications
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