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This strategy has been exploited in the long-acting GLP-1RA semaglutide (Novo Nordisk), for instance, which was approved for treatment of T2DM in 2017, and for treatment of obesity in 2021, and has since then become the most prescribed GLP-1RA 92
This analysis, which may provide a rational judgment on the physicochemical space to optimize oral bioavailability, will be discussed
Finally, dosage is an issue
It does not mean that Retatrutide is approved as a medicine or suitable for human use
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