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However, semaglutide was developed to resist being broken down by these enzymes, which means it lasts much longer in the body
Curr Opin Pharmacol (2013) 13(6):9415.10.1016/j.coph.2013.09.012 148 BermudezRViglianoFQuirogaMINietoJMBosiGDomeneghiniC
In PCOS, rebound could plausibly compromise the stability of metabolic and reproductive gains during the preconception interval, particularly where restoration of ovulatory function appears to depend on sustained improvement in adiposity and insulin resistance
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