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However, accuracy in reconstitution is critical to avoid inadvertent overdose or underdose
Other studies have been performed to unravel the mode of action (MoA) of OTA, for example, to determine if it acts by a DNA-reactive MoA (resulting in mutagenicity) or whether perturbations of other critical cellular processes may explain the non-linear dose response observed in organ- and site-specific tumor development (Mally 2012
Cardiovascular safety trial demonstrating that the DPP-4 inhibitor sitagliptin does not increase MACE or hospitalization for heart failure in patients with T2DM and high cardiovascular risk
doi: 10.1002/jcp.v233.4 101 VilagranICastillo-MartnMPrieto-MartnezNBonetSYesteM
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