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This dose failed to increase her breastmilk carnitine concentration, with a persistently low concentration of 3.4 mg/L (21 micromoles/L) before supplementation and after 18 days of supplementation.[1] The carnitine concentration was measured in the breastmilk of 27 normal mothers who were not taking carnitine as a supplement

doi: 10.1016/j.tcb.2023.07.009

However, there are also some limitations, including the difference in the shape of respective nasal cavities, the exact dosing of intranasal drugs, the mucociliary elimination, and the drainage to the pharynx or to the lower part