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Sergey Terushkin, MD, FACS Clinic: Skin Glow Dermatology, Brooklyn Last Updated: | January 28, 2026 Key Takeaways Dual-Hormone Action: Mounjaro targets both GLP-1 and GIP receptors, making it clinically more potent for weight loss than older single-hormone medications
Some patients have reported symptoms continuing even a year after stopping the medication, as CNN reported
Lowering your dose may reduce dry mouth, but it might also diminish the appetite-suppression effect and slow your weight loss progress
[1] [2] The mechanism by which Ozempic works involves mimicking the action of endogenous GLP-1, which enhances glucose-dependent insulin secretion, suppresses glucagon release, slows gastric emptying, and reduces appetite through central nervous system pathways
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