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For example, athletes with high metabolic demands, vegans who consume no dietary B12, or individuals with chronic malabsorption issues like Crohns disease may find they feel their best with a bi-weekly (every two weeks) injection
Medication use , particularly long-term metformin therapy, proton pump inhibitors, and H2-receptor antagonists, increases deficiency risk
However, its best to check with a healthcare professional before taking high dose vitamin B12 supplements, especially if youre taking other medications or have any underlying health issues
Each comes with its own dosing curve, and researchers who have worked through one titration protocol will find the structure familiar when they approach another
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