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Jusuf, MD, Phd, Prof

The progressive degeneration of neuronal cells that accompanies the decline of memory and other cognitive functions in subjects with Alzheimers disease is associated with an intracellular aggregation of Tau fibrils, an extra-neuronal accumulation of b-amyloid peptides into senile plaques, and an oxidation-reduction (redox) imbalance of complex etiology

Lantibiotic bacteriocins produced by the widespread cariogenic bacterium S.m in the oral cavity have also been shown to perturb the intestinal microbiota, suggesting a direct mechanism by which these oral bacteria contribute to gut dysbiosis (Yonezawa et al., 2021)

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