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Can we give them information to help with that decision? Such tools could have immediate clinical applications

As the body reduces blood flow to non-essential areas to protect vital organs, visible and tactile changes appear: Dry mouth and cracked lips as saliva production drops Skin that tents when pinched and returns slowly to normal a sign of reduced elasticity Sunken eyes and dry, sticky membranes inside the mouth and cheeks Cool, pale, or clammy hands and feet from peripheral vasoconstriction In shock, the skin can become mottled or take on a gray, cyanotic color a grave sign of critically poor tissue oxygenation

Many people do not realize their liver is under stress because the organ has very few pain receptors

Your healthcare team can work with you to find strategies that maximise therapeutic benefits while minimising side effects