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No, GLP-1 receptor agonists are not specifically contraindicated in Crohn's disease, but caution is advised in patients with active or severe gastrointestinal disease

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When to use 10mg versus 5mg vials A 5mg vial makes more sense during early dose escalation (0.25mg to 0.5mg weekly) because you will use less total peptide over the 28-day reconstitution window

The columns were washed with 15 column volumes of buffer 1 followed by the elution with 200 mM imidazole, 50 mM Na x H y PO 4 , 300 mM NaCl, pH 8.0 at 4 C