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In a cytokine storm, pro-oxidants are produced in large quantities

They dont replace the fundamentals of good sleep, adequate protein intake, resistance training, sun protection and avoiding lifestyle factors that prematurely age people

Traditionally, nuclear hormone receptors are ligand-gated transcription factors that orchestrate complex transcriptional programs governing hormonal regulation, sexual differentiation, and metabolism 100,101,102

Moreover, diverse extracellular molecular signals, including neurotransmitters, neurotrophins, extracellular matrix proteins, contact-mediated ligands, and secreted diffusible cues, shape neural circuit development and modulate brain connectivity during early life (Hamad et al., 2023)