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Crdenas-Rodrguez et al., 2014
This does not provide evidence for every pack
Mentioning that you need refrigeration for medication usually gets a prompt response
On the other hand, a vitamin B12 deficiency appears to cause a loss of appetite in some people, leading to weight loss rather than weight gain ( That said, the current evidence is too weak to suggest that a vitamin B12 deficiency has any strong or specific impact on weight be it weight gain or loss
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