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By mitigating oxidative damage in animals exposed to captivity stress or environmental toxins, antioxidants have been used to improve breeding success rates, exemplified by their use in endangered amphibian programs
In cultured fibroblasts, this inhibition suggests regulatory control over cell migration and extracellular matrix remodeling [3]
NFS1 degrades cysteine and releases sulphide, which can be used to generate ironsulphur (FeS) clusters, 138 versatile co-factors that carry out electron transfer, catalysis and afford structural stability
FASEB J 24:25332545 Jones DP (2006) Redefining oxidative stress
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