is wegovy or tirzepatide better vs. Semaglutide for Weight Loss Is Mounjaro Better Than Wegovy?

2019;9(4):e12323

As medications like Zepbound (tirzepatide) help people lose substantial amounts of weight in record time, but researchers are asking a question that I think deserves a lot more attention: Can we lose fat without sacrificing too much muscle

And although Ozempic and Mounjaro have been cleared by the FDA to help with the condition, it has not been approved as a weight loss option, though similar GLP-1 drugs such as semaglutide (Wegovy) and liraglutide (Saxenda) have been approved by the FDA to help treat obesity

doi: 10.1016/j.focha.2025.100919 Summary Keywords alleviating mechanism, gut microbiota, health benefits, live biotherapeutics, next generation probiotics, probiotics Citation El-Saadony MT, Saad AM, Sitohy M, Alkafaas SS, Dladla M, Ghosh S, Mohammed DM, Ibrahim EH, Fahmy MA, Elkelish A, AbuQamar SF and El-Tarabily KA (2026) Probiotics and human health: biological activities, nutritional aspects, immunomodulatory properties, applications, and future perspectives - a comprehensive review