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As a result, many patients experience: Reduced appetite Improved satiety Better metabolic regulation Gradual, sustainable weight loss Semaglutide and tirzepatide are two of the most widely discussed medications in this category
Doing so can increase the risk of side effects, such as nausea, digestive discomfort, or, in rare cases, pancreatitis, without providing extra benefit
Secondary outcome measurements included reduction in body weight from baseline by at least 5% or 10% by week 26, changes in waist circumference, total cholesterol, HDL, LDL, VLDL, and triglycerides, and levels of different glycemic variables including HbA1C, fasting plasma glucose, fasting insulin, insulin resistance, and the functioning of beta-cells
Her thighs looked more disproportionate to her now-smaller torso, but her hip-to-waist measurements actually improved because some of the weight came off the lower torso
