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Nevertheless, although a specific action of homocysteine seems to occur at low concentrations, experimental trials have been conducted only with homocysteine administration, which would reflect a severe hyperhomocysteinemia rather than a more physiologic moderate elevation of circulating homocysteine, and clinical observations have only come from homocystinuric patients with severe hyperhomocysteinemia
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Following solubilization of proteins from midgut tissues and using a filter-aided sample preparation (FASP)-based procedure coupled with mass spectrometric analyses allowed us to identify three sets of proteins enriched in the infected sample vs control: A) Pre-acid treatment
Always consult your personal gastroenterologist before starting or altering any treatment protocol
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