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Researchers observed that BPC-157 is associated with upregulation of growth factor receptor expression, including VEGFR2 and FGFR, which may contribute to its studied effects on angiogenesis
While landmark randomized trials such as RALES [50] and EMPHASIS-HF [51] reported low discontinuation rates of RAASi and mineralocorticoid receptor antagonist (MRA) therapieseven in the setting of hyperkalemiareal-world data suggest otherwise
While these therapies were effective, they resulted in significant side effects and adverse outcomes
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