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| 2003 | ANZ Journal of Surgery Disclaimer: The above information is for research and educational purposes only and not a substitute for professional medical advice

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Given that supplements are concentrated versions of the vitamin, its unclear if foods would have the same effect

2017 meta-analysis: A systematic review and meta-analysis of nine randomized controlled trials showed that ALCAR supplementation significantly decreased depressive symptoms compared to placebo (standardized mean difference 1.10, 95% CI 1.65 to 0.56), with effects comparable to established antidepressants like fluoxetine, particularly in older adults or those with treatment-resistant depression [5][30]