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Therefore, dual GLP-1/glucagon co-agonists, such as survodutide [82], cotadutide [83] and pemvidutide [84] yield greater improvements in hepatic steatosis and fibrosis biomarkers than GLP-1 monotherapy, reflecting additive modulation of mitochondrial and inflammatory pathways
Clinical considerations : Transdermal delivery is often preferred to reduce thrombotic risk
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