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In vitiligo, impaired antioxidant defenses (for example, reduced catalase activity) allow ROS to accumulate, resulting in melanocyte death or malfunction
doi: 10.1038/s41575-020-0331-7 80 FranzosaEASirota-MadiAAvila-PachecoJFornelosNHaiserHJReinkerSet al
GHK-Cu works as a signal, not a drug that forces an outcome
One small study in healthy adults measured a melatonin-related urinary biomarker, but it did not evaluate sleep onset, sleep duration, nighttime awakenings or daytime function
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