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64,65 Cytokine agents such as the CD122 agonist bempegaldesleukin have demonstrated immune-expanding activity in phase I-II trials and restored antitumor responses in B2M-null models when combined with PD-1 blockade in preclinical settings
RNA samples received were quantified using Qubit 2.0 Fluorometer (Life Technologies, Carlsbad, CA, USA), and RNA integrity was checked using Agilent TapeStation 4200 (Agilent Technologies, Palo Alto, CA, USA)
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