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Many individuals may notice improvements in overall skin radiance within 48 weeks, while more visible improvements in skin brightness and even-looking skin tone may take 812 weeks or longer of regular use

Lower levels = less natural defense = more visible skin concerns

The deep evolutionary conservation of molecular and cellular attributes that change during aging between killifish and mammals makes killifish a highly suitable experimental system to test concrete manipulations that can directly affect aging in the immune compartment and that might have practical applications also in mammals, including humans