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Order sedative infusions correctly: If a sedative infusion is being used to control seizures (e.g., propofol), ensure it isnt stopped prematurely during a daily sedation interruption
10.1155/2021/6680935 13 BenameurT.Frota GabanS
Ecotoxicol Environ Saf
Based on these findings, it was recognized for the first time that impairment of antioxidant defenses (vitamin E-deficiency) and enhanced levels of PUFAs (substrates for LPO) did not just amplify the injury mechanism but switched cell death signaling typically centered around mitochondrial dysfunction (in mice on normal diets) to one dominated by acute LPO [70]
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