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Section 1: The Modern API Manufacturing Landscape 1.1 What an API Is, and Why Its Manufacturing Process Is a Core IP Asset An active pharmaceutical ingredient (API) is any substance or mixture of substances that furnishes pharmacological activity or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease

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Although there is a dearth of bioavailability data for many of the peptide nasal sprays, a study showed that direct intratracheal instillation of a lyophilized powder at high concentrations could achieve reasonable levels of systemic absorption [13]

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