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"The Effect of Gastric Bypass on the Pharmacokinetics of Serotonin Reuptake Inhibitors." Am Journ Psychiatry 169.3 (2012): 256263
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The impact of tirzepatide and glucagon-like peptide 1 receptor agonists on absorption of oral hormonal contraceptives
While oral bioavailability is lower than subcutaneous administration, these studies established that even high oral doses maintained excellent safety profiles, though higher doses (54 mg) were associated with increased gastrointestinal discomfort
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