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Semax ist ein von ACTH abgeleitetes Neuropeptid, das vor allem im Kontext von Kognition, Aufmerksamkeit und Neuroprotektion erforscht wird

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While we cannot rule out that the differences in the conformation of the middle loop may come from crystal packing constraints or the allosteric effects from binding to GPCRs 24,25,26,27 , it is tempting to speculate that the larger conformational changes in -strand V upon Src SH3 binding might affect the coupling of arr1 to the receptor and the downstream signaling