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Collectively, these findings highlight the potential of amino acids such as arginine, proline, glutamate, methionine, cysteine, glutamine, and BCAAs as novel biomarkers for IPF diagnosis, disease staging, and progression monitoring

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Even more intriguing are observations which revealed that NF-B and STAT3 factors can form complexes with each other to activate or repress the transcription of target genes either synergistically or through B or STAT3 binding motifs [82, 83]

Additionally, consuming a plant-based diet containing soy, legumes, and quinoa, dietary supplements rich in omega-3 and fermented foods significantly decreases TMAO levels, according to other studies [77, 82]