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Document the clinical rationale per patient in the chart itself: why this compound, why this patient, what you expect to monitor
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While information was found only from one study with 31 mood episodes of 26 patients with bipolar disorder, and 18 controls, it seems that while a depressive phase is associated with a phase delay, a manic phase is associated with a phase advance [53]
and various effects on apoptosis and senescence markers in cell culture
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