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When a peripheral nerve fiber is damaged, the portion of the axon beyond the injury point degenerates through a process called Wallerian degeneration
33 HillP
Importantly however, animal studies collectively emphasize two key principles: first, an adaptive T- and B-cell response can be elicited by myelin that degenerates in a specific way, without any deliberate upregulation of the systemic immune system
91 RanganU.BulkleyG
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