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A study published in the Journal of Endocrinology and Metabolism found that AOD 9604 had no negative impact on blood glucose levels

This enzyme is often overexpressed in adipose tissue in conditions of obesity and metabolic dysfunction, leading to the depletion of nicotinamide and reduced availability of NAD+

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Patients with pre-existing conditions including cardiovascular disease, liver disease, thyroid disorders, kidney disease, or gallbladder disease face particular uncertainty