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According to the incidence, prevalence, and social impact up to 349.2 million individuals were affected by major neurological disorders worldwide (Ding et al., 2022

Clinical data show 57% of cisplatin-treated ovarian cancer patients have moderate-to-severe fatigue, with 27% still experiencing unrelieved symptoms 18 months post-chemotherapy (Beesley et al

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Smoking cessation should be prioritized, as tobacco use promotes systemic inflammation and metabolic dysfunction